New IntOGen web to explore driver genes across cancer types
Coinciding with the publication of our latest paper, on Monday (9 March 2015) (See blog post) we have crafted a new IntOGen interface which presents the results of [...]
In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals novel targeting opportunities
We are pleased to announce the publication of our paper in Cancer Cell describing the landscape of anti-cancer targeted therapeutic opportunities across a cohort of patients of [...]
How to generate mutation distribution and frequency plots?
Let’s plot some mutations! Easy, right? For our next iteration of the IntOGen database, we wanted to add figures that represent the mutation distribution across the protein [...]
OncodriveROLE predicts activating and loss of function cancer driver genes
We are pleased to announce that the Oncodrive methods family has a new member: OncodriveROLE, an approach to classify cancer drivers into loss of function and activating [...]
Molecular subtypes of human cancer
Cancers are typically classified depending on their tissue of origin. However, novel large-scale genomic studies are providing more detailed molecular characterizations of tumors, and thus bring about [...]
How to identify oncogenic driver mutations: a review of bioinformatics approaches
Recently, at least three articles have reviewed the ensemble of bioinformatics tools developed in the past few years to understand the alterations that plague the genome and [...]
Identifying disease related mutations with Condel 2.0
Three years ago, Abel developed and published in the American Journal of Human Genetics an approach to combine the results of several tools aimed at identifying disease-related [...]
Gitools 2.1 visits VizBi
We’d like to communicate two things: We have released a new version of Gitools which brings new capabilities. With these the new Gitools 2.1.0 in the suitcase, [...]
VIZBI 2014: Visualizing Biological Data
Two years ago I attended the VIZBI 2012 to present our latest work on and with Gitools, a tool we use to explore interactive heatmaps of genomics [...]
Our lab receives funding from La Marató de TV3
We are very honored to announce that we have received funds for a 3-year project from the money raised in the last telethon broadcast La Marató de [...]