New Cancer Genome Interpreter Platform
We are excited to announce the release of the new Cancer Genome Interpreter (CGI) Platform, accessible through the updated www.cancergenomeinterpreter.org website. The CGI Platform has been developed [...]
Sex and smoking bias in the selection of somatic mutations in human bladder
Our latest study about somatic mutations in the human bladder is now published in Nature. Using ultradeep DNA duplex sequencing we can measure the clonal landscape of [...]
3D-clustering algorithm for cancer driver gene detection
A new computational method developed in our lab, Oncodrive3D, has been published in Nucleic Acids Research. The article, titled "Oncodrive3D: fast and accurate detection of structural clusters [...]
Five latent factors underlie response to immunotherapy
A study by our group that identified five key factors that are significantly associated with the response of cancer patients to immunotherapy was published in Nature Genetics. [...]
Intogen release 2024
We are very happy to announce that a dual new release of intOGen and boostDM is out. We collected data from 33,218 tumors, resulting in 633 driver [...]
New machine learning models to identify driver mutations for clonal hematopoiesis
Our latest work to identify mutations that drive clonal hematopoiesis (CH) has been published in the journal Cancer Discovery. We developed machine learning models to identify the [...]
Our work on the origin of some pediatric cancers published in Cancer Discovery
We studied the cases of four children who have experienced two cancers during childhood to address the origin of second pediatric cancers. As a tool, the research [...]
Barcelona Biomed Conference on CANCER PROMOTION
CANCER PROMOTION: understanding cancer promotion to inform prevention Link to the video Nuria Lopez-Bigas, jointly with Allan Balmain (UCSF) and Paul Brennan (IARC) is organizing the next [...]
IntOGen new release (2023)
intOGen is out. In this release we have increased the number of cohorts and samples, we have made small updates to the IntOGen pipeline and we have [...]
CGI-CLINICS New Website
We have launched the new website for the EU funded project CGI-Clinics coordinated by Nuria Lopez-Bigas. CGI-Clinics is a community-driven project that aims to improve precision [...]
