CGI-CLINICS New Website
We have launched the new website for the EU funded project CGI-Clinics coordinated by Nuria Lopez-Bigas. CGI-Clinics is a community-driven project that aims to improve precision [...]
CGI-CLINICS Kick Off Meeting
On November 21-23 we celebrated the Kick-Off Meeting of CGI-Clinics, a five-year project funded by the European Commission, which started on November 1st 2022. Sixty participants of [...]
Published in Nature our new machine learning method to analyze cancer driver mutations titled “In Silico saturation mutagenesis of cancer genes”.
BoostDM is a computational tool based on machine learning designed to identify driver mutations affecting cancer genes. The method, inspired in evolutionary biology, is designed to define [...]
Our study about relapse of T-cell acute lymphoblastic leukemia (T-ALL) in adult patients published in Genome Biology
This work performed in collaboration with Hospital del Mar Medical Research Institute and Josep Carreras Leukaemia Research Institute, and supported by Asociación Española Contra el Cáncer [...]
Our review describing IntoGen titled “A compendium of mutational cancer driver genes” published in Nature Reviews Cancer
In this review, we focus on the history of cancer driver genes identification from the beginning of cancer research through the advent of cancer genomics and [...]
Our work on how alterations of ubiquitin-mediated proteolysis affect in cancer published in Nature Cancer
We are very happy to have published one of the first articles of the Nature Cancer journal. We have systematically analyzed how alterations in the ubiquitin proteolysis [...]
Our paper on the mutational footprints of cancer therapies published in Nature Genetics
We are very happy to announce that our manuscript on the mutational footprints of cancer therapies has been published in December's issue of Nature Genetics. In [...]
Our paper on reduced mutation rate in exons due to differential mismatch repair published in Nature Genetics
We are happy to announce that our paper on reduced mutation burden in exons caused by differential mismatch repair has been published yesterday, 6th November in Nature [...]