IntOGen new release (2023)
intOGen is out. In this release we have increased the number of cohorts and samples, we have made small updates to the IntOGen pipeline and we have [...]
intOGen is out. In this release we have increased the number of cohorts and samples, we have made small updates to the IntOGen pipeline and we have [...]
We have launched the new website for the EU funded project CGI-Clinics coordinated by Nuria Lopez-Bigas. CGI-Clinics is a community-driven project that aims to improve precision [...]
On November 21-23 we celebrated the Kick-Off Meeting of CGI-Clinics, a five-year project funded by the European Commission, which started on November 1st 2022. Sixty participants [...]
BoostDM is a computational tool based on machine learning designed to identify driver mutations affecting cancer genes. The method, inspired in evolutionary biology, is designed to define [...]
This work performed in collaboration with Hospital del Mar Medical Research Institute and Josep Carreras Leukaemia Research Institute, and supported by Asociación Española Contra el Cáncer [...]
In this review, we focus on the history of cancer driver genes identification from the beginning of cancer research through the advent of cancer genomics and [...]
We are very happy to have published one of the first articles of the Nature Cancer journal. We have systematically analyzed how alterations in the ubiquitin proteolysis [...]
We are very happy to announce that our manuscript on the mutational footprints of cancer therapies has been published in December's issue of Nature Genetics. In [...]
We are very excited to release a new version of IntOGen, our framework to identify cancer genes and pinpoint putative mechanism of tumorigenesis. The IntOGen website [...]
We are very excited to share that our work describing the somatic and germline 10bp periodicity in the mutation rate within nucleosome-bound DNA was published in the [...]