2023
Mangiante L, ………………………, Gonzalez-Perez A, …………., Lopez-Bigas N,………………………, Foll M & Fernandez-Cuesta L
Nature Genetics doi: 10.1038/s41588-023-01321-1
Gonzalez S, Lopez-Bigas N, Gonzalez-Perez A
PLOS Genetics doi.org/10.1371/journal.pgen.1010634
2022
Arnedo-Pac C, Muiños F, Gonzalez-Perez A, Lopez-Bigas N
Pre-Print, doi: 10.1101/2022.09.14.507952
Pich O, Reyes-Salazar I, Gonzalez-Perez A & Lopez-Bigas N
Nature Communications, doi: 10.1038/s41467-022-31878-0
Arnedo-Pac C, Lopez-Bigas N & Muiños F
Nature Biotechnology, DOI: 10.1038/s41587-021-01187-w
Nadeu F,…, Lopez-Bigas N, …., Campo E
Nature Medicine, DOI:10.1038/s41591-022-01927-8
Palafox M,…, Gonzalez-Perez A,…, Sanchez-Guixé M,…, Lopez-Bigas N, …., Serra V
Nature Communications, DOI: 10.1038/s41467-022-32828-6
Mangiante L, …., Lopez-Bigas N, …., Fernandez-Cuesta L
Journal of Thoracic Oncology, Doi:10.1016/j.jtho.2022.07.029
Anderson CJ,…, Pich O,…, Lopez-Bigas N,…Aikten S
Pre-Print, Doi: 10.1101/2022.06.10.495644
Palles C,…, Arnedo-Pac C,…, Lopez-Bigas N,…, de Voer R.
The American Journal of Human Genetics, DOI: 10.1016/j.ajhg.2022.03.018
2021
Peri A, […] , Arnedo-Pac C, […], Lopez-Bigas N, […], Samuels Y
JCI, doi: 10.1172/JCI129466
Muiños F, Martínez-Jiménez F, Pich O, Gonzalez-Perez A, Lopez-Bigas N
Nature, doi: 10.1038/s41586-021-03771-1
Pich O, Cortes-Bullich A, Muiños F, Pratcorona M, Gonzalez-Perez A & Lopez-Bigas N
Nature Communications, DOI:10.1038/s41467-021-24858-3
Bonet J, Chen M, Dabad M, Heath S, Gonzalez-Perez A, Lopez-Bigas N, Lagergren J
Bioinformatics, doi: 10.1093/bioinformatics/btab745
Frigola J, Sabarinathan R, Gonzalez-Perez A, Lopez-Bigas N
Nucleic Acids Research, DOI:10.1093/nar/gkaa1219
González-Gil C […] , Lopez-Bigas N,[…] Genescà E
Blood doi:10.1182/blood-2021-148263
Zhang T, Joubert, P […] Gonzalez-Perez A, Martínez-Jiménez F, Lopez-Bigas N,[…] Landi MT
Nature Genetics doi:10.1038/s41588-021-00920-0
Aissa AF, Islam ABMMK, Ariss MM, Go CC, Rader AE, Conrardy RD, Gajda AM, Rubio-Perez C, Valyi-Nagy K, Pasquinelli M, Feldman LE, Green SJ, Lopez-Bigas N, Maxim Frolov MV & Benevolenskaya EV
Nature Communications, DOI:10.1038/
Woolston A, Barber LJ, Griffiths B, Pich O, Lopez-Bigas N, Matthews N, Rao S, Watkins D, Chau I, Starling N, Cunningham D & Gerlinger M
Nature Ecology & Evolution, DOI:10.1038/s41559-021-01470-8
2020
Sentís I, Gonzalez S, Genescà E, García-Hernández V, Muiños F, Gonzalez C, López-Arribillaga E, Gonzalez J, Fernandez-Ibarrondo L, Mularoni L, Espinosa LL, Bellosillo B, Ribera JM, Bigas A, Gonzalez-Perez A & Lopez-Bigas N
Genome Biology, DOI:10.1186/s13059-020-02192-z
Martínez-Jiménez F, Muiños F, Sentís I, Deu-Pons J, Reyes-Salazar I, Arnedo-Pac C, Mularoni L, Pich O, Bonet J, Kranas H, Gonzalez-Perez A, Lopez-Bigas N,
Nature Reviews Cancer, DOI: 10.1038/s41568-020-0290-x
McGuire AL, Gabriel S, Tishkoff SA, Wonkam A, Chakravarti A, Furlong EEM , Treutlein B, Meissner A , Chang HY, López- Bigas N, Segal E, Kim JS
Nature Reviews Genetics, DOI: 10.1038/s41576-020-0272-6
Pich O, Cortes-Bullich A, Muiños F, Pratcorona M, Gonzalez-Perez A, Lopez-Bigas N
Preprint DOI:
Pich O, Reyes-Salazar I, Gonzalez-Perez A, Lopez-Bigas N
Preprint DOI:
Martinez-Jimenez F, Muiños F, Lopez-Arribillaga E, Lopez-Bigas N, Gonzalez-Perez A
Nature Cancer doi.org/10.1038/s43018-019-0001-2
Muiños F, Martinez-Jimenez F, Pich O, Gonzalez-Perez A, Lopez-Bigas N
Preprint doi: https://doi.org/10.1101/2020.06.03.130211
Aitken SJ, Anderson CJ, Connor F, Pich O, Sundaram V, Feig C, Rayner TF, Lukk M, Aitken S, Luft J, Kentepozidou E, Arnedo-Pac C, Beentjes S, Davies SE, Drews RM, Ewing A, Kaiser VB, Khamseh A, López-Arribillaga E, Redmond AM, Santoyo-Lopez J, Sentís I, Talmane L, Yates AD, Semple CA, López-Bigas N, Flicek P, Odom DT, Taylor MS
Nature, DOI: 10.1038/s41586-020-2435-1
Borgsmueller N, Bonet J, Marass F, Gonzalez-Perez A, Lopez-Bigas N, Beerenwinkel N
Wagner AH, Walsh B, Mayfield G, Tamborero D, Sonkin D, Krysiak K, Deu-Pons J, Duren RP, Gao J, McMurry J, Patterson S, del Vecchio Fitz C, Pitel BA, Sezerman OU, Ellrott K, Warner JL, Rieke DT, Aittokallio T, Cerami E, Ritter DI, Schriml LM, Freimuth RR, Haendel M, Raca G, Madhavan S, Baudis M, Beckmann JS, Dienstmann R, Chakravarty D, Li XS, Mockus S, Elemento O, Schultz N, Lopez-Bigas N, Lawler M, Goecks J, Griffith M, Griffith OL, A. Margolin AA & Variant Interpretation for Cancer Consortium
Nature Genetics, doi: 10.1038/s41588-020-0603-8
Alexandrov LB, Kim J, Haradhvala NJ, Huang MN, Tian Ng AW, Wu Y, Boot A, Covington KR, Gordenin DA, Bergstrom EN, Islam SMA, Lopez-Bigas N, Klimczak LJ, McPherson JR, Morganella S, Sabarinathan R, Wheeler DA, Mustonen V; PCAWG Mutational Signatures Working Group, Getz G, Rozen SG, Stratton MR; PCAWG Consortium.
Nature, doi: 10.1038/s41586-020-1943-3
Rheinbay E et al. , including Sabarinathan R, Mularoni L, Gonzalez-Perez A, Pich O, Tamborero D, López-Bigas N; PCAWG Consortium.
Nature, doi: 10.1038/s41586-020-1965-x
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, including
Nature, doi: 10.1038/s41586-020-1969-6
2019
Arnedo-Pac C, Mularoni L, Muiños F, Gonzalez-Perez A, Lopez-Bigas N
Pich O, Muiños F, Lolkema MP, Steeghs N, Gonzalez-Perez A, Lopez-Bigas N
Gonzalez-Perez A, Sabarinathan R, Lopez-Bigas N
Cell DOI:10.1016/j.cell.2019.02.051
Hernández-Sánchez M, Kotaskova J, Rodríguez AE, Radova L, Tamborero D, Abáigar M, Plevova K, Benito R, Tom N, Quijada-Álamo M, Bikos V, Martín AÁ, Pal K, García de Coca A, Doubek M, López-Bigas N, Hernández-Rivas JM, Pospisilova S.
Leukemia. doi: 10.1038/s41375-018-0255-1
2018
Pich O, Muiños F, Sabarinathan R, Reyes-Salazar I, Gonzalez-Perez A, Lopez-Bigas N
Cell doi:10.1016/j.cell.2018.10.004
Tamborero D, Rubio-Perez C, Deu-Pons J, Schroeder MP, Vivancos A, Rovira A, Tusquets I, Albanell J, Rodon J, Tabernero J, de Torres C, Dienstmann R, Gonzalez-Perez A, Lopez-Bigas N
Genome Medicine doi: 10.1186/s13073-018-0531-8
A pan-cancer landscape of interactions between solid tumors and infiltrating immune cell populations
Tamborero D, Rubio-Perez C, Muinos F, Sabarinathan R, Piulats JMM, Muntasell A, Dientsmann R, Lopez-Bigas N, Gonzalez-Perez A
Clinical Cancer Research doi:10.1158/1078-0432.CCR-17-3509
Mateo J, Chakravarty D, Dienstmann R, Jezdic S, Gonzalez-Perez A, Lopez-Bigas N, Ng CKY, Bedard PL, Tortora G, Douillard JY, Van Allen EM, Schultz N, Swanton C, André F, Pusztai L.
Annals of Oncology. 2018 doi: 10.1093/annonc/mdy263.
Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Ng PK, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortés-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H; MC3 Working Group; Cancer Genome Atlas Research Network, Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J, Wheeler D, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L.
Cell. 2018 doi: 10.1016/j.cell.2018.02.060.
Martínez-Ricarte F, Mayor R, Martínez-Sáez E, Rubio-Pérez C, Pineda E, Cordero E, Cicuéndez M, Poca MA, López-Bigas N, Ramon Y Cajal S, Vieito M, Carles J, Tabernero J, Vivancos A, Gallego S, Graus F, Sahuquillo J, Seoane J.
Clinical Cancer Research. 2018 doi: 10.1158/1078-0432.CCR-17-3800.
2017
Frigola J, Sabarinathan R, Mularoni L, Muiños F, Gonzalez-Perez A, López-Bigas N
Nature Genetics doi:10.1038/ng.3991
Sabarinathan R, Pich O, Martincorena I, Rubio-Perez C, Juul M, Wala J, Schumacher S, Shapira O, Sidiropoulos N, Waszak S, Tamborero D, Mularoni L, Rheinbay E, Hornshoj H, Deu-Pons J, Muinos F, Bertl J, Guo Q, Weischenfeldt J, Korbel JO, Getz G, Campbell PJ, Pedersen JS, Beroukhim R, Perez-Gonzalez A, Lopez-Bigas N, PCAWG Drivers and Functional Interpretation Group, ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Net
Preprint doi: 10.1101/190330
Griffith M, Spies NC, Krysiak K, McMichael JF, Coffman AC, Danos AM, Ainscough BJ, Ramirez CA, Rieke DT, Kujan L, Barnell EK, Wagner AH, Skidmore ZL, Wollam A, Liu CJ, Jones MR, Bilski RL, Lesurf R, Feng Y, Shah NM, Bonakdar M, Trani L, Matlock M, Ramu A, Campbell KM, Spies GC, Graubert AP, Gangavarapu K, Eldred JM, Larson DE, Walker JR, Good BM, Wu C, Su AI, Dienstmann R, Margolin A, Tamborero D, Lopez-Bigas N, Jones SJM, Bose R, Spencer DH, Wartman LD, Wilson RK, Mardis ER, Griffith OL.
Nature Genetics, 2017 doi:10.1038/ng.3774
Hayward NK, Wilmott JS, Waddell N, Johansson PA, Field MA, Nones K, Patch AM, Kakavand H, Alexandrov LB, Burke H, Jakrot V, Kazakoff S, Holmes O, Leonard C, Sabarinathan R, Mularoni L, Wood S, Xu Q, Waddell N, Tembe V, Pupo GM, De Paoli-Iseppi R, Vilain RE, Shang P, Lau LMS, Dagg RA, Schramm SJ, Pritchard A, Dutton-Regester K, Newell F, Fitzgerald A, Shang CA, Grimmond SM, Pickett HA, Yang JY, Stretch JR, Behren A, Kefford RF, Hersey P, Long GV, Cebon J, Shackleton M, Spillane AJ, Saw RPM, López-Bigas N, Pearson JV, Thompson JF, Scolyer RA, Mann GJ
Nature, 2017 doi:10.1038/nature22071
Karube K, Enjuanes A, Dlouhy I, Jares P, Martin-Garcia D, Nadeu F, Ordóñez GR, Rovira J, Clot G, Royo C, Navarro A, Gonzalez-Farre B, Vaghefi A, Castellano G, Rubio-Perez C, Tamborero D, Briones J, Salar A, Sancho JM, Mercadal S, Gonzalez-Barca E, Escoda L0, Miyoshi H, Ohshima K, Miyawaki K, Kato K, Akashi K, Mozos A, Colomo L, Alcoceba M, Valera A, Carrió A, Costa D, Lopez-Bigas N, Schmitz R, Staudt LM, Salaverria I, López-Guillermo A, Campo E
Leukemia. 2017 DOI: 10.1038/leu.2017.251
Porta-Pardo E, Kamburov A, Tamborero D, Pons T, Grases D, Valencia A, Lopez-Bigas N, Getz G, Godzik A
Nat Methods. 2017. doi: 10.1038/nmeth.4364.
2016
Carlota Rubio-Perez, Jordi Deu-Pons, David Tamborero, Nuria Lopez-Bigas, Abel Gonzalez-Perez
Genome Medicine 2016 8:98, DOI: 10.1186/s13073-016-0349-1
Radhakrishnan Sabarinathan, Loris Mularoni, Jordi Deu-Pons, Abel Gonzalez-Perez, Nuria Lopez-Bigas
Nature 2016, 532, 264-267 (14 April 2016) doi:10.1038/nature17661
Frigola J, Iturbide A, Lopez-Bigas N, Peiro S, Gonzalez-Perez A.
Oncotarget. 2016 Apr 15. doi:10.18632/oncotarget.8752.
Iorio F*, Knijnenburg TA*, Vis DJ*, Bignell GR*, Menden MP*, Schubert M, Aben N, Gonçalves E, Barthorpe S, Lightfoot H, Greninger P, van Dyk E, Chang H, de Silva H, Heyn HA, Deng X, Egan RK, Liu Q, Mironenko T, Mitropoulos X, Richardson L, Wang J, Zhang T, Moran S, Saylos S, Soleimani M, Tamborero D, Lopez-Bigas N, Ross-Macdonald P, Esteller M, Gray N, Haber DA, Stratton MR, Benes CH, Wessels LFA+, Saez-Rodriguez J+, McDermott U+, Garnett MJ+
Cell 166, 1-15, 2016
Loris Mularoni, Radhakrishnan Sabarinathan, Jordi Deu-Pons, Abel Gonzalez-Perez, Núria López-Bigas.
Genome Biology, 2016 17:128 DOI: 10.1186/s13059-016-0994-0
Mateo F et al.
Oncogene 2016 doi: 10.1038/onc.2016.427
2015
Carlota Rubio-Perez#, David Tamborero#, Michael P. Schroeder, Albert A. Antolin, Jordi Deu-Pons, Christian Perez-Llamas, Jordi Mestres, Abel Gonzalez-Perez#, Nuria Lopez-Bigas#
Cancer Cell 27 (2015), pp. 382-396
Puente XS, Beà S, Valdés-Mas R, Villamor N, Gutiérrez-Abril J, Martín-Subero JI, Munar M, Rubio-Pérez C, Jares P, Aymerich M, Baumann T, Beekman R, Belver L, Carrio A, Castellano G, Clot G, Colado E, Colomer D, Costa D, Delgado J, Enjuanes A, Estivill X, Ferrando AA, Gelpí JL, González B, González S, González M, Gut M, Hernández-Rivas JM, López-Guerra M, Martín-García D, Navarro A, Nicolás P, Orozco M, Payer ÁR, Pinyol M, Pisano DG, Puente DA, Queirós AC, Quesada V, Romeo-Casabona CM, Royo C, Royo R, Rozman M, Russiñol N, Salaverría I, Stamatopoulos K, Stunnenberg HG, Tamborero D, Terol MJ, Valencia A, López-Bigas N, Torrents D, Gut I, López-Guillermo A, López-Otín C, Campo E
Nature. 2015 Jul 22. doi: 10.1038/nature14666.
Mutation Consequences and Pathway Analysis working group of the International Cancer Genome Consortium.
Nat Methods. 2015 Jun 30;12(7):615-21. doi: 10.1038/nmeth.3440.
Gallardo F, Padrón A, Garcia-Carbonell R, Rius C, González-Perez A, Arumí-Uria M, Iglesias M, Nonell L, Bellosillo B, Segura S, Pujol RM, Lopez-Bigas N, Bertran J, Bigas A, Espinosa L.
Oncotarget. 2015 Apr 20;6(11):9284-94.
Leiserson MD, Vandin F, Wu HT, Dobson JR, Eldridge JV, Thomas JL, Papoutsaki A, Kim Y, Niu B, McLellan M, Lawrence MS, Gonzalez-Perez A, Tamborero D, Cheng Y, Ryslik GA, Lopez-Bigas N, Getz G, Ding L, Raphael BJ.
Nat Genet. 2015 Feb;47(2):106-14. doi: 10.1038/ng.3168. Epub 2014 Dec 15.
Chiara Di Vona, Daniela Bezdan, Abul BMMK Islam, Eulàlia Salichs, Nuria López-Bigas, Stephan Ossows, Susana de la Luna
Molecular Cell 57 (2015), pp. 506-520
B Barneda-Zahonero, O Collazo, A Azagra, I Fernández-Duran, J Serra-Musach, Abul BMMK Islam, N Vega-García, R Malatesta, M Camós, A Gómez, L Román-González, AVidal, N López-Bigas , A Villanueva, M Esteller, M Parra
Cell death & disease 6 (2), e1635