Open Position for a Bioinformatician (ref. LAB/19/11)
We are searching for a highly motivated bioinformatician to work in our Research Group. The position is to work on the development of bioinformatics tools and pipelines [...]
Our latest release of intOGen now available online!
We are very excited to release a new version of IntOGen, our framework to identify cancer genes and pinpoint putative mechanism of tumorigenesis. The IntOGen website [...]
Our paper on how nucleosomes influence mutation rate leading to a 10bp periodic pattern is out in Cell
We are very excited to share that our work describing the somatic and germline 10bp periodicity in the mutation rate within nucleosome-bound DNA was published in the [...]
Introducing the Cancer Genome Interpreter
This is a post written by Abel, Carlota, David and Nuria for BioMed Central blog network Cancer Genome Interpreter (CGI) is an open platform designed to support the [...]
Our paper on reduced mutation rate in exons due to differential mismatch repair published in Nature Genetics
We are happy to announce that our paper on reduced mutation burden in exons caused by differential mismatch repair has been published yesterday, 6th November in Nature [...]
We have moved to Institute for Research in Biomedicine (IRB Barcelona)!
This is the first week of our lab at the IRB. We are excited and eager to start working here and interacting with the new colleagues. The [...]
Thanks University Pompeu Fabra (UPF). Thanks Barcelona Biomedical Research Park (PRBB).
Today is the last day of my group at UPF and the PRBB after more than 10 years. We are moving to the Barcelona Institute for [...]
A Cancer Genome Interpreter to identify driver and actionable alterations in tumors
The use of genomic information is becoming a key piece of the oncology toolkit to make informed decisions aimed to improve the management of the disease and increase the cost-effectiveness of available therapies.
Our paper demonstrating that proteins bound to DNA impair Nucleotide Excision Repair published in Nature
I am very happy to announce that our manuscript describing the increased mutation rate in Transcription Factor Binding Sites (TFBS) in melanomas and lung tumors has been published in today's issue of Nature. In the manuscript we demonstrate that this accumulation is due to the impairment of Nucleotide Excision Repair (NER) activity by proteins bound to DNA.
ERC-consolidator granted to our lab to find noncoding cancer drivers
We are happy to announce that our lab has been awarded an European Research Council Consolidator Grant. ERC-consolidator grants are designed “To fund top researchers of any nationality and [...]