2 open positions for postdoctoral researchers
We are searching for 2 highly motivated Postdoctoral Researchers to work on projects analyzing somatic mutations in whole-genomes and/or single cell sequencing data with the aim [...]
Published in Nature our new machine learning method to analyze cancer driver mutations titled “In Silico saturation mutagenesis of cancer genes”.
BoostDM is a computational tool based on machine learning designed to identify driver mutations affecting cancer genes. The method, inspired in evolutionary biology, is designed to define [...]
Our study about relapse of T-cell acute lymphoblastic leukemia (T-ALL) in adult patients published in Genome Biology
This work performed in collaboration with Hospital del Mar Medical Research Institute and Josep Carreras Leukaemia Research Institute, and supported by Asociación Española Contra el Cáncer [...]
Our review describing IntoGen titled “A compendium of mutational cancer driver genes” published in Nature Reviews Cancer
In this review, we focus on the history of cancer driver genes identification from the beginning of cancer research through the advent of cancer genomics and [...]
Our work on how alterations of ubiquitin-mediated proteolysis affect in cancer published in Nature Cancer
We are very happy to have published one of the first articles of the Nature Cancer journal. We have systematically analyzed how alterations in the ubiquitin proteolysis [...]
Our paper on the mutational footprints of cancer therapies published in Nature Genetics
We are very happy to announce that our manuscript on the mutational footprints of cancer therapies has been published in December's issue of Nature Genetics. In [...]
Our latest release of intOGen now available online!
We are very excited to release a new version of IntOGen, our framework to identify cancer genes and pinpoint putative mechanism of tumorigenesis. The IntOGen website [...]
Our paper on how nucleosomes influence mutation rate leading to a 10bp periodic pattern is out in Cell
We are very excited to share that our work describing the somatic and germline 10bp periodicity in the mutation rate within nucleosome-bound DNA was published in the [...]
Introducing the Cancer Genome Interpreter
This is a post written by Abel, Carlota, David and Nuria for BioMed Central blog network Cancer Genome Interpreter (CGI) is an open platform designed to support the [...]
Our paper on reduced mutation rate in exons due to differential mismatch repair published in Nature Genetics
We are happy to announce that our paper on reduced mutation burden in exons caused by differential mismatch repair has been published yesterday, 6th November in Nature [...]