From IRB Barcelona


From our Lab

  • March 20, 2024

    Our work on the origin of some pediatric cancers published in Cancer Discovery

    We studied the cases of four children who have experienced two cancers during childhood to address the origin of second pediatric cancers. As a tool, the research uses [...]

  • February 2, 2024

    Barcelona Biomed Conference on CANCER PROMOTION

    CANCER PROMOTION: understanding cancer promotion to inform prevention Nuria Lopez-Bigas, jointly with Allan Balmain (UCSF) and Paul Brennan (IARC) is organizing the next Barcelona Biomed Conference that will [...]

  • June 2, 2023

    IntOGen new release (2023)

    intOGen is out. In this release we have increased the number of cohorts and samples, we have made small updates to the IntOGen pipeline and we have updated [...]

  • March 17, 2023

    CGI-CLINICS New Website

    We have launched the new website for the EU funded project CGI-Clinics coordinated by Nuria Lopez-Bigas. CGI-Clinics is a community-driven project that aims to improve precision medicine [...]

  • November 28, 2022

    CGI-CLINICS Kick Off Meeting

    On November 21-23 we celebrated the Kick-Off Meeting of CGI-Clinics, a five-year project funded by the European Commission, which started on November 1st 2022. Sixty participants of [...]

  • July 30, 2021

    Published in Nature our new machine learning method to analyze cancer driver mutations titled “In Silico saturation mutagenesis of cancer genes”.

    BoostDM is a computational tool based on machine learning designed to identify driver mutations affecting cancer genes. The method, inspired in evolutionary biology, is designed to define the [...]

  • December 17, 2020

    Our study about relapse of T-cell acute lymphoblastic leukemia (T-ALL) in adult patients published in Genome Biology

    This work performed in collaboration with Hospital del Mar Medical Research Institute and Josep Carreras Leukaemia Research Institute, and supported by Asociación Española Contra el Cáncer (AECC), [...]

  • September 2, 2020

    Our review describing IntoGen titled “A compendium of mutational cancer driver genes” published in Nature Reviews Cancer

    In this review, we focus on the history of cancer driver genes identification from the beginning of cancer research through the advent of cancer genomics and into [...]

  • December 16, 2019

    Our work on how alterations of ubiquitin-mediated proteolysis affect in cancer published in Nature Cancer

    We are very happy to have published one of the first articles of the Nature Cancer journal. We have systematically analyzed how alterations in the ubiquitin proteolysis system [...]

  • December 12, 2019

    Our paper on the mutational footprints of cancer therapies published in Nature Genetics

    We are very happy to announce that our manuscript on the mutational footprints of cancer therapies has been published in December's issue of Nature Genetics. In this [...]