BoostDM is a computational tool based on machine learning designed to identify driver mutations affecting cancer genes. The method, inspired in evolutionary biology, is designed to define [...]
This work performed in collaboration with Hospital del Mar Medical Research Institute and Josep Carreras Leukaemia Research Institute, and supported by Asociación Española Contra el Cáncer [...]
In this review, we focus on the history of cancer driver genes identification from the beginning of cancer research through the advent of cancer genomics and [...]
We are very happy to have published one of the first articles of the Nature Cancer journal. We have systematically analyzed how alterations in the ubiquitin proteolysis [...]
We are very happy to announce that our manuscript on the mutational footprints of cancer therapies has been published in December's issue of Nature Genetics. In [...]
We are very excited to release a new version of IntOGen, our framework to identify cancer genes and pinpoint putative mechanism of tumorigenesis. The IntOGen website [...]
We are very excited to share that our work describing the somatic and germline 10bp periodicity in the mutation rate within nucleosome-bound DNA was published in the [...]
This is a post written by Abel, Carlota, David and Nuria for BioMed Central blog network Cancer Genome Interpreter (CGI) is an open platform designed to support the [...]
We are happy to announce that our paper on reduced mutation burden in exons caused by differential mismatch repair has been published yesterday, 6th November in Nature [...]
This is the first week of our lab at the IRB. We are excited and eager to start working here and interacting with the new colleagues. The [...]