• March 30, 2018

    Introducing the Cancer Genome Interpreter

    This is a post written by Abel, Carlota, David and Nuria for BioMed Central blog network Cancer Genome Interpreter (CGI) is an open platform designed to support the identification [...]

  • November 7, 2017

    Our paper on reduced mutation rate in exons due to differential mismatch repair published in Nature Genetics

    We are happy to announce that our paper on reduced mutation burden in exons caused by differential mismatch repair has been published yesterday, 6th November in Nature Genetics. [...]

  • November 2, 2016

    We have moved to Institute for Research in Biomedicine (IRB Barcelona)!

    This is the first week of our lab at the IRB. We are excited and eager to start working here and interacting with the new colleagues. The IRB [...]

  • October 28, 2016

    Thanks University Pompeu Fabra (UPF). Thanks Barcelona Biomedical Research Park (PRBB).

    Today is the last day of my group at UPF and the PRBB after more than 10 years. We are moving to the Barcelona Institute for Research [...]

  • October 5, 2016

    A Cancer Genome Interpreter to identify driver and actionable alterations in tumors

    The use of genomic information is becoming a key piece of the oncology toolkit to make informed decisions aimed to improve the management of the disease and increase the cost-effectiveness of available therapies.

  • April 14, 2016

    Our paper demonstrating that proteins bound to DNA impair Nucleotide Excision Repair published in Nature

    I am very happy to announce that our manuscript describing the increased mutation rate in Transcription Factor Binding Sites (TFBS) in melanomas and lung tumors has been published in today's issue of Nature. In the manuscript we demonstrate that this accumulation is due to the impairment of Nucleotide Excision Repair (NER) activity by proteins bound to DNA.

  • February 4, 2016

    ERC-consolidator granted to our lab to find noncoding cancer drivers

    We are happy to announce that our lab has been awarded an European Research Council Consolidator Grant. ERC-consolidator grants are designed “To fund top researchers of any nationality and age, [...]

  • March 17, 2015

    New IntOGen web to explore driver genes across cancer types

    Coinciding with the publication of our latest paper, on Monday (9 March 2015) (See blog post) we have crafted a new IntOGen interface which presents the results of the [...]

  • March 9, 2015

    In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals novel targeting opportunities

    We are pleased to announce the publication of our paper in Cancer Cell describing the landscape of anti-cancer targeted therapeutic opportunities across a cohort of patients of twenty [...]

  • December 19, 2014

    How to generate mutation distribution and frequency plots?

    Let’s plot some mutations! Easy, right? For our next iteration of the IntOGen database, we wanted to add figures that represent the mutation distribution across the protein sequence. [...]