Our latest release of intOGen now available online!
We are very excited to release a new version of IntOGen, our framework to identify cancer genes and pinpoint putative mechanism of tumorigenesis. The IntOGen website [...]
Our paper on how nucleosomes influence mutation rate leading to a 10bp periodic pattern is out in Cell
We are very excited to share that our work describing the somatic and germline 10bp periodicity in the mutation rate within nucleosome-bound DNA was published in the [...]
Mutual exclusion statistics and data events in Gitools
We’re pleased to announce another incremental release of Gitools, version 2.2. Amongst the many improvements (listed at the bottom of this post) we’d like to highlight the [...]
My slides on: Identification of cancer drivers across tumor types
Yesterday I gave a talk at the PRBB Computational Genomics Seminars Series. In that talk I summarized our work of this year in the lab. Basically, we [...]
How to visualize multidimensional cancer genomics data?
A challenge to all cancer genomic studies is to visually explore the generated complex data in a meaningful way to extract relevant knowledge. We have written a review on [...]
How to identify cancer drivers from tumor somatic mutations?
I have recently seen several presentations by groups that systematically explore alterations in cancer genomes that deliver the same message. One of the main challenges [...]
Exploring multiple cancer genomics alterations with Gitools.
Cancer genomics data that is produced creates multi-dimensional data sets. Gitools lets you browse all that data at once. A typical cancer genomics project nowadays [...]
Abel wins the Poster Prize at EMBO Cancer Genomics meeting
Abel and I have been three days at the EMBO Cancer Genomics meeting that was held in Heidelberg. I have to say that the meeting was very inspiring [...]