Five latent factors underlie response to immunotherapy
A study by our group that identified five key factors that are significantly associated with the response of cancer patients to immunotherapy was published in Nature Genetics. [...]
Intogen release 2024
We are very happy to announce that a dual new release of intOGen and boostDM is out. We collected data from 33,218 tumors, resulting in 633 driver [...]
New machine learning models to identify driver mutations for clonal hematopoiesis
Our latest work to identify mutations that drive clonal hematopoiesis (CH) has been published in the journal Cancer Discovery. We developed machine learning models to identify the [...]
Our work on the origin of some pediatric cancers published in Cancer Discovery
We studied the cases of four children who have experienced two cancers during childhood to address the origin of second pediatric cancers. As a tool, the research [...]
Barcelona Biomed Conference on CANCER PROMOTION
CANCER PROMOTION: understanding cancer promotion to inform prevention Link to the video Nuria Lopez-Bigas, jointly with Allan Balmain (UCSF) and Paul Brennan (IARC) is organizing the next [...]
IntOGen new release (2023)
intOGen is out. In this release we have increased the number of cohorts and samples, we have made small updates to the IntOGen pipeline and we have [...]
CGI-CLINICS New Website
We have launched the new website for the EU funded project CGI-Clinics coordinated by Nuria Lopez-Bigas. CGI-Clinics is a community-driven project that aims to improve precision [...]
CGI-CLINICS Kick Off Meeting
On November 21-23 we celebrated the Kick-Off Meeting of CGI-Clinics, a five-year project funded by the European Commission, which started on November 1st 2022. Sixty participants [...]
Published in Nature our new machine learning method to analyze cancer driver mutations titled “In Silico saturation mutagenesis of cancer genes”.
BoostDM is a computational tool based on machine learning designed to identify driver mutations affecting cancer genes. The method, inspired in evolutionary biology, is designed to define [...]
Our study about relapse of T-cell acute lymphoblastic leukemia (T-ALL) in adult patients published in Genome Biology
This work performed in collaboration with Hospital del Mar Medical Research Institute and Josep Carreras Leukaemia Research Institute, and supported by Asociación Española Contra el Cáncer [...]
