Sex and smoking bias in the selection of somatic mutations in human bladder
Our latest study about somatic mutations in the human bladder is now published in Nature. Using ultradeep DNA duplex sequencing we can measure the clonal landscape of normal [...]
August 25, 2025
3D-clustering algorithm for cancer driver gene detection
A new computational method developed in our lab, Oncodrive3D, has been published in Nucleic Acids Research. The article, titled "Oncodrive3D: fast and accurate detection of structural clusters of [...]
October 1, 2024
Five latent factors underlie response to immunotherapy
A study by our group that identified five key factors that are significantly associated with the response of cancer patients to immunotherapy was published in Nature Genetics. We [...]
September 23, 2024
Intogen release 2024
We are very happy to announce that a dual new release of intOGen and boostDM is out. We collected data from 33,218 tumors, resulting in 633 driver genes. [...]
September 18, 2024
New machine learning models to identify driver mutations for clonal hematopoiesis
Our latest work to identify mutations that drive clonal hematopoiesis (CH) has been published in the journal Cancer Discovery. We developed machine learning models to identify the mutations [...]
March 20, 2024
Our work on the origin of some pediatric cancers published in Cancer Discovery
We studied the cases of four children who have experienced two cancers during childhood to address the origin of second pediatric cancers. As a tool, the research uses [...]
February 2, 2024
Barcelona Biomed Conference on CANCER PROMOTION
CANCER PROMOTION: understanding cancer promotion to inform prevention Link to the video Nuria Lopez-Bigas, jointly with Allan Balmain (UCSF) and Paul Brennan (IARC) is organizing the next Barcelona [...]
June 2, 2023
IntOGen new release (2023)
intOGen is out. In this release we have increased the number of cohorts and samples, we have made small updates to the IntOGen pipeline and we have updated [...]
March 17, 2023
CGI-CLINICS New Website
We have launched the new website for the EU funded project CGI-Clinics coordinated by Nuria Lopez-Bigas. CGI-Clinics is a community-driven project that aims to improve precision medicine [...]
November 28, 2022
CGI-CLINICS Kick Off Meeting
On November 21-23 we celebrated the Kick-Off Meeting of CGI-Clinics, a five-year project funded by the European Commission, which started on November 1st 2022. Sixty participants of [...]