How to prioritize cancer somatic mutations?
Projects that sequence the genomes of a cohort of tumor samples are faced with the challenge of deciding which somatic mutations are relevant to tumor development (drivers). [...]
Systematic identification of cancer drivers across tumor types in IntOGen
This post is to share with you the poster describing “Systematic identification of cancer drivers across tumor types in IntOGen” that was presented last week at the Cambridge [...]
TransFIC and OncodriveFM: Tools for the analysis of cancer sequencing data
This post is to share with you the poster describing “TransFIC and OncodriveFM: Tools for the analysis of cancer sequencing data” that was presented last week at [...]
How does full repression of cell cycle gene occur during differentiation ?
The ability of the retinoblastoma protein (pRB) to restrict the cell cycle is well known. Since KDM5A/RBP2/JARID1A is associated with pRB/E2F, one may wonder about its recruitment [...]
Gitools 1.7.0: The new features
We have been preparing a new version of Gitools with many improvements, amongst which there is a new IGV search, the use of categorical scales and new [...]
IntOGen V.04: with somatic mutations from cancer genome sequencing projects
We are proud to share with you the Beta version of IntOGen V.04 at http://beta.intogen.org. This new version includes many changes both in content and in layout. [...]
Modifications in condel server
Several weeks ago we realized we were having problems retrieving the functional impact scores from the MutationAssessor webservice into our condel web server. We immediately corrected the [...]
Awards from UPF to members of our lab
Members of our lab received yesterday two awards from the Social Council of the University Pompeu Fabra. […]
How to identify cancer drivers from tumor somatic mutations?
I have recently seen several presentations by groups that systematically explore alterations in cancer genomes that deliver the same message. One of the main challenges [...]