Identifying disease related mutations with Condel 2.0
Three years ago, Abel developed and published in the American Journal of Human Genetics an approach to combine the results of several tools aimed at identifying disease-related [...]
New IntOGen Somatic Mutations Analysis version available
We are proud to announce the brand new version of the IntOGen Somatic Mutations Analysis (IntOGen SM) pipeline. We call it version 2.0.0 as it has been completely [...]
Condel for prioritization of variants involved in hereditary diseases and transFIC for cancer
We have worked during the last years on assessing the functional impact of non-synonymous variants (nsSNVs). As a result, we have published two new approaches Condel and [...]
How to evaluate the performance of computational methods to identify driver mutations?
We have recently published transFIC, a computational method to assess the functional impact of somatic cancer mutations (see this post). To evaluate the performance of transFIC we [...]
How to prioritize cancer somatic mutations?
Projects that sequence the genomes of a cohort of tumor samples are faced with the challenge of deciding which somatic mutations are relevant to tumor development (drivers). [...]
TransFIC and OncodriveFM: Tools for the analysis of cancer sequencing data
This post is to share with you the poster describing “TransFIC and OncodriveFM: Tools for the analysis of cancer sequencing data” that was presented last week at [...]
