Our research is focused on the study of cancer from a genomics perspective. We are particularly interested in the identification of cancer driver mutations, genes and pathways across tumour types and in the study of the mutational processes across tissues and genomic regions.

Mutational Processes

Finding drivers
of cancer

Contribute precision
cancer medicine

Contribute to precision cancer medicine

The possibility to associate the alterations observed in a patient’s tumour with suitable anti-cancer therapies relies heavily on our ability to accurately identify the alterations that drive the malignancy, as well as those that predict its sensitivity or resistance to drugs.

Our lab seeks to contribute to the advancement of precision medicine, in particular the interpretation of the genomic variants of tumours, thus facilitating the identification of therapeutic options for cancer patients.

Towards this aim, we have developed (CGI) a tool designed to support the identification of tumor alterations that drive the disease and/or which may be therapeutically actionable. We are currently working in the EU project together with multiple clinical european partners.