News

  • October 10, 2025

    Sex and smoking bias in the selection of somatic mutations in human bladder

    Our latest study about somatic mutations in the human bladder is now published in Nature. Using ultradeep DNA duplex sequencing we can measure the clonal landscape of normal [...]

  • August 25, 2025

    3D-clustering algorithm for cancer driver gene detection

    A new computational method developed in our lab, Oncodrive3D, has been published [...]

  • October 1, 2024

    Five latent factors underlie response to immunotherapy

    A study by our group that identified five key factors that are [...]

Research

Understanding
Mutational Processes

Finding drivers
of cancer

Contribute precision
cancer medicine

Studying clonal expansions
in normal tissues

Publications

  • Origins of Second Malignancies in Children and Mutational Footprint of Chemotherapy in Normal Tissues

  • Identification of Clonal Hematopoiesis Driver Mutations through In Silico Saturation Mutagenesis

  • Sex and smoking bias in the selection of somatic mutations in human bladder