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Select cancer type cohort
Mandatory to select one
Format: VEP mutational output
Select candidate genes
Mandatory Validate to Submit
Format: Gene symbols comma separated
Format: one gene symbol per line
Fine tune the genes/regions to include in the panel
Specify a panel size
Include/exclude panel gene candidates
*Only if one of the pre-compiled gene lists was selected as input
Specify if you want to force including one/several genes into the panel candidates
Format: gene symbols comma separated
File format: one gene symbol per line
Specify if you want to force excluding one/several genes from the panel candidates
Fine tune panel tier gene classification
In this section you can modify the gene tier classification method.
Fine tune gene regions parameters
In this section you can fine-tune the detection of gene fragments to include in the panel.
of the mutations in a gene are demanded to be allocated in mutation high density regions, modify this parameter here.
Specify which genes are to be included entirely instead of broken down into fragments (by default only TP53 is included entirely):
Gene symbols comma separated
*One gene symbol per line
In this section you can fine-tune whether genes are included in full or by specific regions of high mutation density in the panel.
Specify if some genes should be included as whole genes and not regions in the panel (by default only TP53 is included whole gene):
Tick to include all genes in the panel as whole genes, do not consider gene regions.
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