Publications
Sánchez-Guixé M, Muiños F, Pinheiro-Santin M, González-Huici V, Rodriguez-Hernandez CJ, Avgustinova A, Lavarino C, González-Pérez A, Mora J, López-Bigas N
Cancer Discovery, doi.org/10.1158/2159-8290.CD-23-1186
Ramos-Rodriguez M,…..,López-Bigas N….,Gonzalez-Perez A , ..Pascuali L
Pre-print biorXiv, Doi: 10.1101/2024.01.23.576802
Demajo S, Ramis-Zaldivar JE, Grau ML, Andrianova M, Muiños F, López-Bigas N, Gonzalez-Perez A
Pre-print MedRxiv DOI: 10.1101/2023.12.13.23299893Arnedo-Pac C, Muiños F, Gonzalez-Perez A, López-Bigas N
Mol Syst Biol DOI: 10.1038/s44320-023-00001-wAbbas S, Pich O, Devonshire G, Zamani SA, Katz-Summercorn A, Killcoyne S, Cheah C, Nutzinger B, Grehan N, Lopez-Bigas N, Fitzgerald RC, Secrier M
Nature Comm doi: 10.1038/s41467-023-39957-6Gonzalez S, Lopez-Bigas N, Gonzalez-Perez A
PLOS Genetics doi.org/10.1371/journal.pgen.1010634Mangiante L, ………………………, Gonzalez-Perez A, …………., Lopez-Bigas N,………………………, Foll M & Fernandez-Cuesta L
Nature Genetics doi: 10.1038/s41588-023-01321-1
Palles C,…, Arnedo-Pac C,…, Lopez-Bigas N,…, de Voer R.
The American Journal of Human Genetics, DOI: 10.1016/j.ajhg.2022.03.018Anderson CJ,…, Pich O,…, Lopez-Bigas N,…Aikten S
Pre-Print, Doi: 10.1101/2022.06.10.495644Mangiante L, …., Lopez-Bigas N, …., Fernandez-Cuesta L
Journal of Thoracic Oncology, Doi:10.1016/j.jtho.2022.07.029Palafox M,…, Gonzalez-Perez A,…, Sanchez-Guixé M,…, Lopez-Bigas N, …., Serra V
Nature Communications, DOI: 10.1038/s41467-022-32828-6Nadeu F,…, Lopez-Bigas N, …., Campo E
Nature Medicine, DOI:10.1038/s41591-022-01927-8Arnedo-Pac C, Lopez-Bigas N & Muiños F
Nature Biotechnology, DOI: 10.1038/s41587-021-01187-wPich O, Reyes-Salazar I, Gonzalez-Perez A & Lopez-Bigas N
Nature Communications, doi: 10.1038/s41467-022-31878-0Arnedo-Pac C, Muiños F, Gonzalez-Perez A, Lopez-Bigas N
Pre-Print, doi: 10.1101/2022.09.14.507952
Woolston A, Barber LJ, Griffiths B, Pich O, Lopez-Bigas N, Matthews N, Rao S, Watkins D, Chau I, Starling N, Cunningham D & Gerlinger M
Nature Ecology & Evolution, DOI:10.1038/s41559-021-01470-8
Aissa AF, Islam ABMMK, Ariss MM, Go CC, Rader AE, Conrardy RD, Gajda AM, Rubio-Perez C, Valyi-Nagy K, Pasquinelli M, Feldman LE, Green SJ, Lopez-Bigas N, Maxim Frolov MV & Benevolenskaya EV
Nature Communications, DOI:10.1038/s41467-021-21884-z González-Gil C […] , Lopez-Bigas N,[…] Genescà E
Blood doi:10.1182/blood-2021-148263Frigola J, Sabarinathan R, Gonzalez-Perez A, Lopez-Bigas N
Nucleic Acids Research, DOI:10.1093/nar/gkaa1219Bonet J, Chen M, Dabad M, Heath S, Gonzalez-Perez A, Lopez-Bigas N, Lagergren J
Bioinformatics, doi: 10.1093/bioinformatics/btab745
Pich O, Cortes-Bullich A, Muiños F, Pratcorona M, Gonzalez-Perez A & Lopez-Bigas N
Nature Communications, DOI:10.1038/s41467-021-24858-3Muiños F, Martínez-Jiménez F, Pich O, Gonzalez-Perez A, Lopez-Bigas N
Nature, doi: 10.1038/s41586-021-03771-1Peri A, […] , Arnedo-Pac C, […], Lopez-Bigas N, […], Samuels Y
JCI, doi: 10.1172/JCI129466
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, including
Nature, doi: 10.1038/s41586-020-1969-6Rheinbay E et al. , including Sabarinathan R, Mularoni L, Gonzalez-Perez A, Pich O, Tamborero D, López-Bigas N; PCAWG Consortium.
Nature, doi: 10.1038/s41586-020-1965-xAlexandrov LB, Kim J, Haradhvala NJ, Huang MN, Tian Ng AW, Wu Y, Boot A, Covington KR, Gordenin DA, Bergstrom EN, Islam SMA, Lopez-Bigas N, Klimczak LJ, McPherson JR, Morganella S, Sabarinathan R, Wheeler DA, Mustonen V; PCAWG Mutational Signatures Working Group, Getz G, Rozen SG, Stratton MR; PCAWG Consortium.
Nature, doi: 10.1038/s41586-020-1943-3Wagner AH, Walsh B, Mayfield G, Tamborero D, Sonkin D, Krysiak K, Deu-Pons J, Duren RP, Gao J, McMurry J, Patterson S, del Vecchio Fitz C, Pitel BA, Sezerman OU, Ellrott K, Warner JL, Rieke DT, Aittokallio T, Cerami E, Ritter DI, Schriml LM, Freimuth RR, Haendel M, Raca G, Madhavan S, Baudis M, Beckmann JS, Dienstmann R, Chakravarty D, Li XS, Mockus S, Elemento O, Schultz N, Lopez-Bigas N, Lawler M, Goecks J, Griffith M, Griffith OL, A. Margolin AA & Variant Interpretation for Cancer Consortium
Nature Genetics, doi: 10.1038/s41588-020-0603-8Borgsmueller N, Bonet J, Marass F, Gonzalez-Perez A, Lopez-Bigas N, Beerenwinkel N
Bioinformatics, DOI:10.1093/bioinformatics/btaa599Aitken SJ, Anderson CJ, Connor F, Pich O, Sundaram V, Feig C, Rayner TF, Lukk M, Aitken S, Luft J, Kentepozidou E, Arnedo-Pac C, Beentjes S, Davies SE, Drews RM, Ewing A, Kaiser VB, Khamseh A, López-Arribillaga E, Redmond AM, Santoyo-Lopez J, Sentís I, Talmane L, Yates AD, Semple CA, López-Bigas N, Flicek P, Odom DT, Taylor MS
Nature, DOI: 10.1038/s41586-020-2435-1Martinez-Jimenez F, Muiños F, Lopez-Arribillaga E, Lopez-Bigas N, Gonzalez-Perez A
Nature Cancer doi.org/10.1038/s43018-019-0001-2PDF Article Preprint in Biorxiv Behind the Paper Nature Cancer News and Views
Pich O, Reyes-Salazar I, Gonzalez-Perez A, Lopez-Bigas N
Preprint DOI:McGuire AL, Gabriel S, Tishkoff SA, Wonkam A, Chakravarti A, Furlong EEM , Treutlein B, Meissner A , Chang HY, López- Bigas N, Segal E, Kim JS
Nature Reviews Genetics, DOI: 10.1038/s41576-020-0272-6Sentís I, Gonzalez S, Genescà E, García-Hernández V, Muiños F, Gonzalez C, López-Arribillaga E, Gonzalez J, Fernandez-Ibarrondo L, Mularoni L, Espinosa LL, Bellosillo B, Ribera JM, Bigas A, Gonzalez-Perez A & Lopez-Bigas N
Genome Biology, DOI:10.1186/s13059-020-02192-zMartínez-Jiménez F, Muiños F, Sentís I, Deu-Pons J, Reyes-Salazar I, Arnedo-Pac C, Mularoni L, Pich O, Bonet J, Kranas H, Gonzalez-Perez A, Lopez-Bigas N,
Nature Reviews Cancer, DOI: 10.1038/s41568-020-0290-x
Hernández-Sánchez M, Kotaskova J, Rodríguez AE, Radova L, Tamborero D, Abáigar M, Plevova K, Benito R, Tom N, Quijada-Álamo M, Bikos V, Martín AÁ, Pal K, García de Coca A, Doubek M, López-Bigas N, Hernández-Rivas JM, Pospisilova S.
Leukemia. doi: 10.1038/s41375-018-0255-1Gonzalez-Perez A, Sabarinathan R, Lopez-Bigas N
Cell DOI:10.1016/j.cell.2019.02.051Pich O, Muiños F, Lolkema MP, Steeghs N, Gonzalez-Perez A, Lopez-Bigas N
Nature Genetics. doi: https://doi.org/10.1101/683268PDF Article Preprint in Biorxiv Behind the Paper Highlight in Nature Medicine
Arnedo-Pac C, Mularoni L, Muiños F, Gonzalez-Perez A, Lopez-Bigas N
Bioinformatics doi: 10.1093/bioinformatics/btz501
Martínez-Ricarte F, Mayor R, Martínez-Sáez E, Rubio-Pérez C, Pineda E, Cordero E, Cicuéndez M, Poca MA, López-Bigas N, Ramon Y Cajal S, Vieito M, Carles J, Tabernero J, Vivancos A, Gallego S, Graus F, Sahuquillo J, Seoane J.
Clinical Cancer Research. 2018 doi: 10.1158/1078-0432.CCR-17-3800.Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Ng PK, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortés-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H; MC3 Working Group; Cancer Genome Atlas Research Network, Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J, Wheeler D, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L.
Cell. 2018 doi: 10.1016/j.cell.2018.02.060.Mateo J, Chakravarty D, Dienstmann R, Jezdic S, Gonzalez-Perez A, Lopez-Bigas N, Ng CKY, Bedard PL, Tortora G, Douillard JY, Van Allen EM, Schultz N, Swanton C, André F, Pusztai L.
Annals of Oncology. 2018 doi: 10.1093/annonc/mdy263.A pan-cancer landscape of interactions between solid tumors and infiltrating immune cell populations
Tamborero D, Rubio-Perez C, Muinos F, Sabarinathan R, Piulats JMM, Muntasell A, Dientsmann R, Lopez-Bigas N, Gonzalez-Perez A
Clinical Cancer Research doi:10.1158/1078-0432.CCR-17-3509Tamborero D, Rubio-Perez C, Deu-Pons J, Schroeder MP, Vivancos A, Rovira A, Tusquets I, Albanell J, Rodon J, Tabernero J, de Torres C, Dienstmann R, Gonzalez-Perez A, Lopez-Bigas N
Genome Medicine doi: 10.1186/s13073-018-0531-8Pich O, Muiños F, Sabarinathan R, Reyes-Salazar I, Gonzalez-Perez A, Lopez-Bigas N
Cell doi:10.1016/j.cell.2018.10.004
Porta-Pardo E, Kamburov A, Tamborero D, Pons T, Grases D, Valencia A, Lopez-Bigas N, Getz G, Godzik A
Nat Methods. 2017. doi: 10.1038/nmeth.4364.Karube K, Enjuanes A, Dlouhy I, Jares P, Martin-Garcia D, Nadeu F, Ordóñez GR, Rovira J, Clot G, Royo C, Navarro A, Gonzalez-Farre B, Vaghefi A, Castellano G, Rubio-Perez C, Tamborero D, Briones J, Salar A, Sancho JM, Mercadal S, Gonzalez-Barca E, Escoda L0, Miyoshi H, Ohshima K, Miyawaki K, Kato K, Akashi K, Mozos A, Colomo L, Alcoceba M, Valera A, Carrió A, Costa D, Lopez-Bigas N, Schmitz R, Staudt LM, Salaverria I, López-Guillermo A, Campo E
Leukemia. 2017 DOI: 10.1038/leu.2017.251Hayward NK, Wilmott JS, Waddell N, Johansson PA, Field MA, Nones K, Patch AM, Kakavand H, Alexandrov LB, Burke H, Jakrot V, Kazakoff S, Holmes O, Leonard C, Sabarinathan R, Mularoni L, Wood S, Xu Q, Waddell N, Tembe V, Pupo GM, De Paoli-Iseppi R, Vilain RE, Shang P, Lau LMS, Dagg RA, Schramm SJ, Pritchard A, Dutton-Regester K, Newell F, Fitzgerald A, Shang CA, Grimmond SM, Pickett HA, Yang JY, Stretch JR, Behren A, Kefford RF, Hersey P, Long GV, Cebon J, Shackleton M, Spillane AJ, Saw RPM, López-Bigas N, Pearson JV, Thompson JF, Scolyer RA, Mann GJ
Nature, 2017 doi:10.1038/nature22071Griffith M, Spies NC, Krysiak K, McMichael JF, Coffman AC, Danos AM, Ainscough BJ, Ramirez CA, Rieke DT, Kujan L, Barnell EK, Wagner AH, Skidmore ZL, Wollam A, Liu CJ, Jones MR, Bilski RL, Lesurf R, Feng Y, Shah NM, Bonakdar M, Trani L, Matlock M, Ramu A, Campbell KM, Spies GC, Graubert AP, Gangavarapu K, Eldred JM, Larson DE, Walker JR, Good BM, Wu C, Su AI, Dienstmann R, Margolin A, Tamborero D, Lopez-Bigas N, Jones SJM, Bose R, Spencer DH, Wartman LD, Wilson RK, Mardis ER, Griffith OL.
Nature Genetics, 2017 doi:10.1038/ng.3774Sabarinathan R, Pich O, Martincorena I, Rubio-Perez C, Juul M, Wala J, Schumacher S, Shapira O, Sidiropoulos N, Waszak S, Tamborero D, Mularoni L, Rheinbay E, Hornshoj H, Deu-Pons J, Muinos F, Bertl J, Guo Q, Weischenfeldt J, Korbel JO, Getz G, Campbell PJ, Pedersen JS, Beroukhim R, Perez-Gonzalez A, Lopez-Bigas N, PCAWG Drivers and Functional Interpretation Group, ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Net
Preprint doi: 10.1101/190330Frigola J, Sabarinathan R, Mularoni L, Muiños F, Gonzalez-Perez A, López-Bigas N
Nature Genetics doi:10.1038/ng.3991NATURE GENETICS NEWS & VIEWS CELL SYSTEMS: Principles of Systems Biology PDF Article
Mateo F et al.
Oncogene 2016 doi: 10.1038/onc.2016.427Loris Mularoni, Radhakrishnan Sabarinathan, Jordi Deu-Pons, Abel Gonzalez-Perez, Núria López-Bigas.
Genome Biology, 2016 17:128 DOI: 10.1186/s13059-016-0994-0Iorio F*, Knijnenburg TA*, Vis DJ*, Bignell GR*, Menden MP*, Schubert M, Aben N, Gonçalves E, Barthorpe S, Lightfoot H, Greninger P, van Dyk E, Chang H, de Silva H, Heyn HA, Deng X, Egan RK, Liu Q, Mironenko T, Mitropoulos X, Richardson L, Wang J, Zhang T, Moran S, Saylos S, Soleimani M, Tamborero D, Lopez-Bigas N, Ross-Macdonald P, Esteller M, Gray N, Haber DA, Stratton MR, Benes CH, Wessels LFA+, Saez-Rodriguez J+, McDermott U+, Garnett MJ+
Cell 166, 1-15, 2016Frigola J, Iturbide A, Lopez-Bigas N, Peiro S, Gonzalez-Perez A.
Oncotarget. 2016 Apr 15. doi:10.18632/oncotarget.8752.Radhakrishnan Sabarinathan, Loris Mularoni, Jordi Deu-Pons, Abel Gonzalez-Perez, Nuria Lopez-Bigas
Nature 2016, 532, 264-267 (14 April 2016) doi:10.1038/nature17661Carlota Rubio-Perez, Jordi Deu-Pons, David Tamborero, Nuria Lopez-Bigas, Abel Gonzalez-Perez
Genome Medicine 2016 8:98, DOI: 10.1186/s13073-016-0349-1
B Barneda-Zahonero, O Collazo, A Azagra, I Fernández-Duran, J Serra-Musach, Abul BMMK Islam, N Vega-García, R Malatesta, M Camós, A Gómez, L Román-González, AVidal, N López-Bigas , A Villanueva, M Esteller, M Parra
Cell death & disease 6 (2), e1635Chiara Di Vona, Daniela Bezdan, Abul BMMK Islam, Eulàlia Salichs, Nuria López-Bigas, Stephan Ossows, Susana de la Luna
Molecular Cell 57 (2015), pp. 506-520Leiserson MD, Vandin F, Wu HT, Dobson JR, Eldridge JV, Thomas JL, Papoutsaki A, Kim Y, Niu B, McLellan M, Lawrence MS, Gonzalez-Perez A, Tamborero D, Cheng Y, Ryslik GA, Lopez-Bigas N, Getz G, Ding L, Raphael BJ.
Nat Genet. 2015 Feb;47(2):106-14. doi: 10.1038/ng.3168. Epub 2014 Dec 15.Gallardo F, Padrón A, Garcia-Carbonell R, Rius C, González-Perez A, Arumí-Uria M, Iglesias M, Nonell L, Bellosillo B, Segura S, Pujol RM, Lopez-Bigas N, Bertran J, Bigas A, Espinosa L.
Oncotarget. 2015 Apr 20;6(11):9284-94.Mutation Consequences and Pathway Analysis working group of the International Cancer Genome Consortium.
Nat Methods. 2015 Jun 30;12(7):615-21. doi: 10.1038/nmeth.3440.Puente XS, Beà S, Valdés-Mas R, Villamor N, Gutiérrez-Abril J, Martín-Subero JI, Munar M, Rubio-Pérez C, Jares P, Aymerich M, Baumann T, Beekman R, Belver L, Carrio A, Castellano G, Clot G, Colado E, Colomer D, Costa D, Delgado J, Enjuanes A, Estivill X, Ferrando AA, Gelpí JL, González B, González S, González M, Gut M, Hernández-Rivas JM, López-Guerra M, Martín-García D, Navarro A, Nicolás P, Orozco M, Payer ÁR, Pinyol M, Pisano DG, Puente DA, Queirós AC, Quesada V, Romeo-Casabona CM, Royo C, Royo R, Rozman M, Russiñol N, Salaverría I, Stamatopoulos K, Stunnenberg HG, Tamborero D, Terol MJ, Valencia A, López-Bigas N, Torrents D, Gut I, López-Guillermo A, López-Otín C, Campo E
Nature. 2015 Jul 22. doi: 10.1038/nature14666.Carlota Rubio-Perez#, David Tamborero#, Michael P. Schroeder, Albert A. Antolin, Jordi Deu-Pons, Christian Perez-Llamas, Jordi Mestres, Abel Gonzalez-Perez#, Nuria Lopez-Bigas#
Cancer Cell 27 (2015), pp. 382-396PDF Article Blog post about this manuscript Research highlight in Nature Reviews Drug Discovery Highlight in research watch of cancer discovery Science translational medicine editor’s choice
