How to identify cancer drivers from tumor somatic mutations?
I have recently seen several presentations by groups that systematically explore alterations in cancer genomes that deliver the same message. One of the main challenges [...]
I have recently seen several presentations by groups that systematically explore alterations in cancer genomes that deliver the same message. One of the main challenges [...]
I am happy to announce the Barcelona Summer School in Genomics and Bioinformatics, which will take place from September 17th to 21st 2012. The course [...]
Khademul Islam, full name Abul Bashar Mir Mohammad Khademul Islam, defended his Thesis work on Monday. He delivered a 50 minutes presentation followed by 1h and 15 minutes [...]
14-3-3σ is an adaptor protein that regulates multiple signal transduction pathways. It has been described as a tumour suppressor in breast cancer, where it is often lost [...]
As you may have read in the last post, Günes and Nuria presented the Sample Level Enrichment Analysis (SLEA) as a methodology to analyse the transcription level [...]
We are happy to share with you the results of a new publication, which has been published today in Genome Medicine: Gunes Gundem and Nuria Lopez-Bigas. Sample [...]
This year our lab will participate again in the Gulbenkian Training Program in Bioinformatics (GTPB). Abel and Michael will give a 3 days course on Bioinformatics [...]
We announce today a new release of Gitools, version 1.6.1. A few bugs have been fixed and some of them are important, so we recommend to update [...]
Cancer cells often exhibit a change in number of copies of certain genomic regions when compared to normal cells (Copy Number Alterations: CNAs). Some of these CNAs [...]
On the quest to identify cancer driver genes, it has been observed that driver alterations that affect a pathway tend to be altered in a mutually exclusive manner. [...]