We have worked during the last years on assessing the functional impact of non-synonymous variants (nsSNVs). As a result, we have published two new approaches Condel and [...]
We have recently published transFIC, a computational method to assess the functional impact of somatic cancer mutations (see this post). To evaluate the performance of transFIC we [...]
Projects that sequence the genomes of a cohort of tumor samples are faced with the challenge of deciding which somatic mutations are relevant to tumor development (drivers). [...]
This post is to share with you the poster describing “Systematic identification of cancer drivers across tumor types in IntOGen” that was presented last week at the Cambridge [...]
This post is to share with you the poster describing “TransFIC and OncodriveFM: Tools for the analysis of cancer sequencing data” that was presented last week at [...]
The ability of the retinoblastoma protein (pRB) to restrict the cell cycle is well known. Since KDM5A/RBP2/JARID1A is associated with pRB/E2F, one may wonder about its recruitment [...]
We have been preparing a new version of Gitools with many improvements, amongst which there is a new IGV search, the use of categorical scales and new [...]
We are proud to share with you the Beta version of IntOGen V.04 at http://beta.intogen.org. This new version includes many changes both in content and in layout. [...]
Several weeks ago we realized we were having problems retrieving the functional impact scores from the MutationAssessor webservice into our condel web server. We immediately corrected the [...]
Members of our lab received yesterday two awards from the Social Council of the University Pompeu Fabra. […]
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